Immune signature of Chlamydia vaccine CTH522/CAF®01 translates from mouse-to-human and induces durable protection in mice

Abstract The clinical development of an effective Chlamydia vaccine requires in-depth understanding of how well protective pre-clinical immune signatures translate to humans. Here, we report a comparative immunological characterization of CTH522/CAF®01 in female mice and humans. We find a range of i...

Full description

Saved in:
Bibliographic Details
Main Authors: Anja Weinreich Olsen, Ida Rosenkrands, Christina S. Jacobsen, Hannah M. Cheeseman, Max P Kristiansen, Jes Dietrich, Robin J. Shattock, Frank Follmann
Format: Artigo
Language:English
Published: 2024
Online Access:https://doi.org/10.1038/s41467-024-45526-2
https://www.nature.com/articles/s41467-024-45526-2.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!