SURGE: uncovering context-specific genetic-regulation of gene expression from single-cell RNA sequencing using latent-factor models
Abstract Genetic regulation of gene expression is a complex process, with genetic effects known to vary across cellular contexts such as cell types and environmental conditions. We developed SURGE, a method for unsupervised discovery of context-specific expression quantitative trait loci (eQTLs) fro...
Сохранить в:
| Главные авторы: | , , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | английский |
| Опубликовано: |
2024
|
| Online-ссылка: | https://doi.org/10.1186/s13059-023-03152-z https://genomebiology.biomedcentral.com/counter/pdf/10.1186/s13059-023-03152-z |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|