Discovery of dual-active ethionamide boosters inhibiting the Mycobacterium tuberculosis ESX-1 secretion system
Drug-resistant Mycobacterium tuberculosis (Mtb) remains a major public health concern requiring complementary approaches to standard anti-tuberculous regimens. Anti-virulence molecules or compounds that enhance the activity of antimicrobial prodrugs are promising alternatives to conventional antibio...
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Auteurs principaux: | , , , , , , , , , , , , |
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Format: | Artigo |
Langue: | anglais |
Publié: |
2024
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Accès en ligne: | https://doi.org/10.1016/j.chembiol.2023.12.007 |
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