BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state

BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state

Abstract ATP-dependent chromatin remodeling SWI/SNF complexes exist in three subcomplexes: canonical BAF (cBAF), polybromo BAF (PBAF), and a newly described non-canonical BAF (ncBAF). While cBAF and PBAF regulate fates of multiple cell types, roles for ncBAF in hematopoietic stem cells (HSCs) have n...

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Main Authors: Muran Xiao, Shinji Kondo, Masaki Nomura, Shinichiro Kato, Koutarou Nishimura, Weijia Zang, Yifan Zhang, Tomohiro Akashi, Aaron D. Viny, Tsukasa Shigehiro, Tomokatsu Ikawa, Hiromi Yamazaki, Miki Fukumoto, Atsushi Tanaka, Yasutaka Hayashi, Yui Koike, Yumi Aoyama, Hiromi Ito, Hiroyoshi Nishikawa, Toshio Kitamura, Akinori Kanai, Akihiko Yokoyama, Tohru Fujiwara, Susumu Goyama, Hideki Noguchi, Stanley Chun-Wei Lee, Atsushi Toyoda, Kunihiko Hinohara, Omar Abdel‐Wahab, Daichi Inoue
Format: Artigo
Language:English
Published: 2023
Online Access:https://doi.org/10.1038/s41467-023-44081-6
https://www.nature.com/articles/s41467-023-44081-6.pdf
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https://doi.org/10.1038/s41467-023-44081-6
https://www.nature.com/articles/s41467-023-44081-6.pdf

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