Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals

Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals

Problematic alcohol use (PAU), a trait that combines alcohol use disorder and alcohol-related problems assessed with a questionnaire, is a leading cause of death and morbidity worldwide. Here we conducted a large cross-ancestry meta-analysis of PAU in 1,079,947 individuals (European, N = 903,147; Af...

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Huvudupphovsmän: Hang Zhou, Rachel L. Kember, Joseph D. Deak, Heng Xu, Sylvanus Toikumo, Kai Yuan, Penelope A. Lind, Leila Farajzadeh, Lu Wang, Alexander S. Hatoum, Jessica Johnson, Hyunjoon Lee, Travis T. Mallard, Jiayi Xu, Keira J.A. Johnston, Emma C. Johnson, Trine Tollerup Nielsen, Marco Galimberti, Cecilia Dao, Daniel F. Levey, Cassie Overstreet, Enda M. Byrne, Nathan A. Gillespie, Scott D. Gordon, Ian B. Hickie, John B. Whitfield, Ke Xu, Hongyu Zhao, Laura M. Huckins, Lea K. Davis, Sandra Sanchez‐Roige, Pamela A. F. Madden, Andrew C. Heath, Sarah E. Medland, Nicholas G. Martin, Tian Ge, Jordan W. Smoller, David M. Hougaard, Anders D. Børglum, Ditte Demontis, John H. Krystal, J. Michael Gaziano, Howard J. Edenberg, Arpana Agrawal, Amy C. Justice, Murray B. Stein, Henry R. Kranzler, Joel Gelernter
Materialtyp: Artigo
Språk:engelska
Publicerad: 2023
Länkar:https://doi.org/10.1038/s41591-023-02653-5
https://www.nature.com/articles/s41591-023-02653-5.pdf
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https://doi.org/10.1038/s41591-023-02653-5
https://www.nature.com/articles/s41591-023-02653-5.pdf

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