Senescent Schwann cells induced by aging and chronic denervation impair axonal regeneration following peripheral nerve injury

Abstract Following peripheral nerve injury, successful axonal growth and functional recovery require Schwann cell (SC) reprogramming into a reparative phenotype, a process dependent upon c‐Jun transcription factor activation. Unfortunately, axonal regeneration is greatly impaired in aged organisms a...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Andrés Flores, Cristian Gerónimo‐Olvera, Karina do Carmo de Vasconcelos Girardi, David Ñecuñir, Sandip Kumar Patel, Joanna Bons, Megan C. Wright, Daniel H. Geschwind, Ahmet Höke, Jose A. Gomez‐Sanchez, Birgit Schilling, Daniela L. Rebolledo, Judith Campisi, Felipe A. Court
Formatua: Artigo
Hizkuntza:ingelesa
Argitaratua: 2023
Sarrera elektronikoa:https://doi.org/10.15252/emmm.202317907
https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/emmm.202317907
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