Stowaways in the cargo: Contaminating nucleic acids in rAAV preparations for gene therapy
Recombinant AAV (rAAV) is the most used delivery vector for clinical gene therapy. However, many issues must be addressed before safer and more widespread implementation can be achieved. At present, efficacies are highly variable across trials and patients, and immune responses after treatment are w...
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| Main Authors: | , , |
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| 格式: | Revisão |
| 语言: | 英语 |
| 出版: |
2023
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| 在线阅读: | https://doi.org/10.1016/j.ymthe.2023.07.025 https://www.cell.com/article/S152500162300432X/pdf |
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