Stowaways in the cargo: Contaminating nucleic acids in rAAV preparations for gene therapy

Recombinant AAV (rAAV) is the most used delivery vector for clinical gene therapy. However, many issues must be addressed before safer and more widespread implementation can be achieved. At present, efficacies are highly variable across trials and patients, and immune responses after treatment are w...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Mark A. Brimble, Stephen M. Winston, Andrew M. Davidoff
स्वरूप: Revisão
भाषा:अंग्रेज़ी
प्रकाशित: 2023
ऑनलाइन पहुंच:https://doi.org/10.1016/j.ymthe.2023.07.025
https://www.cell.com/article/S152500162300432X/pdf
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