Reframing the link between metabolism and NLRP3 inflammasome: therapeutic opportunities

Reframing the link between metabolism and NLRP3 inflammasome: therapeutic opportunities

Inflammasomes are multiprotein signaling platforms in the cytosol that senses exogenous and endogenous danger signals and respond with the maturation and secretion of IL-1β and IL-18 and pyroptosis to induce inflammation and protect the host. The inflammasome best studied is the Nucleotide-binding o...

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Autores principales: Miguel Á. Ortega, Diego De León-Oliva, Cielo García‐Montero, Oscar Fraile‐Martínez, Diego Liviu Boaru, Amador Velazquez de Castro, Miguel A. Sáez, Laura López-González, Julia Buján, Miguel Ángel Alvarez-Mon, Natalio García‐Honduvilla, Raúl Dı́az, Melchor Álvarez‐Mon
Formato: Revisão
Lenguaje:inglés
Publicado: 2023
Acceso en línea:https://doi.org/10.3389/fimmu.2023.1232629
https://www.frontiersin.org/articles/10.3389/fimmu.2023.1232629/pdf
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https://doi.org/10.3389/fimmu.2023.1232629
https://www.frontiersin.org/articles/10.3389/fimmu.2023.1232629/pdf

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