TomoTwin: generalized 3D localization of macromolecules in cryo-electron tomograms with structural data mining

Cryogenic-electron tomography enables the visualization of cellular environments in extreme detail, however, tools to analyze the full amount of information contained within these densely packed volumes are still needed. Detailed analysis of macromolecules through subtomogram averaging requires part...

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Autori principali: Gavin Rice, Thorsten Wagner, Markus Stabrin, Oleg Sitsel, Daniel Prumbaum, Stefan Raunser
Natura: Artigo
Lingua:inglese
Pubblicazione: 2023
Accesso online:https://doi.org/10.1038/s41592-023-01878-z
https://www.nature.com/articles/s41592-023-01878-z.pdf
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