A kinesin‐based approach for inducing chromosome‐specific mis‐segregation in human cells

Abstract Various cancer types exhibit characteristic and recurrent aneuploidy patterns. The origins of these cancer type‐specific karyotypes are still unknown, partly because introducing or eliminating specific chromosomes in human cells still poses a challenge. Here, we describe a novel strategy to...

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Main Authors: My Anh Truong, Paula Cané‐Gasull, Sippe G. de Vries, Wilco Nijenhuis, René Wardenaar, Lukas C. Kapitein, Floris Foijer, Susanne M.A. Lens
格式: Artigo
语言:英语
出版: 2023
在线阅读:https://doi.org/10.15252/embj.2022111559
https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/embj.2022111559
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