A kinesin‐based approach for inducing chromosome‐specific mis‐segregation in human cells

Abstract Various cancer types exhibit characteristic and recurrent aneuploidy patterns. The origins of these cancer type‐specific karyotypes are still unknown, partly because introducing or eliminating specific chromosomes in human cells still poses a challenge. Here, we describe a novel strategy to...

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Bibliographic Details
Main Authors: My Anh Truong, Paula Cané‐Gasull, Sippe G. de Vries, Wilco Nijenhuis, René Wardenaar, Lukas C. Kapitein, Floris Foijer, Susanne M.A. Lens
Format: Artigo
Language:English
Published: 2023
Online Access:https://doi.org/10.15252/embj.2022111559
https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/embj.2022111559
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