Targeting of the Mon1-Ccz1 Rab guanine nucleotide exchange factor to distinct organelles by a synergistic protein and lipid code
Activation of the small GTPase Rab7 by its cognate guanine nucleotide exchange factor Mon1-Ccz1 (MC1) is a key step in the maturation of endosomes and autophagosomes. This process is tightly regulated and subject to precise spatiotemporal control of MC1 localization, but the mechanisms that underly...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2023
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| Online Access: | https://doi.org/10.1016/j.jbc.2023.102915 http://www.jbc.org/article/S0021925823000479/pdf |
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