Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer’s disease
Abstract Human middle temporal gyrus (MTG) is a vulnerable brain region in early Alzheimer’s disease (AD), but little is known about the molecular mechanisms underlying this regional vulnerability. Here we utilize the 10 × Visium platform to define the spatial transcriptomic profile in both AD and c...
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Үндсэн зохиолчид: | , , , , , , , , , , , , , , , , , , , |
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Формат: | Artigo |
Хэл сонгох: | англи |
Хэвлэсэн: |
2022
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Онлайн хандалт: | https://doi.org/10.1186/s40478-022-01494-6 https://actaneurocomms.biomedcentral.com/counter/pdf/10.1186/s40478-022-01494-6 |
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