Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer’s disease

Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer’s disease

Abstract Human middle temporal gyrus (MTG) is a vulnerable brain region in early Alzheimer’s disease (AD), but little is known about the molecular mechanisms underlying this regional vulnerability. Here we utilize the 10 × Visium platform to define the spatial transcriptomic profile in both AD and c...

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Bibliografische gegevens
Hoofdauteurs: Shuo Chen, Yuzhou Chang, Liangping Li, Diana Acosta, Yang Li, Qi Guo, Cankun Wang, Emir Turkes, Cody Morrison, Dominic Julian, Mark E. Hester, Douglas W. Scharre, Chintda Santiskulvong, Sarah XueYing Song, Jasmine Plummer, Geidy E. Serrano, Thomas G. Beach, Karen Duff, Qin Ma, Hongjun Fu
Formaat: Artigo
Taal:Engels
Gepubliceerd in: 2022
Online toegang:https://doi.org/10.1186/s40478-022-01494-6
https://actaneurocomms.biomedcentral.com/counter/pdf/10.1186/s40478-022-01494-6
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https://doi.org/10.1186/s40478-022-01494-6
https://actaneurocomms.biomedcentral.com/counter/pdf/10.1186/s40478-022-01494-6

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