Culture impact on the transcriptomic programs of primary and iPSC-derived human alveolar type 2 cells
Dysfunction of alveolar epithelial type 2 cells (AEC2s), the facultative progenitors of lung alveoli, is implicated in pulmonary disease pathogenesis, highlighting the importance of human in vitro models. However, AEC2-like cells in culture have yet to be directly compared to their in vivo counterpa...
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| Autori principali: | , , , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | inglese |
| Pubblicazione: |
2022
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| Accesso online: | https://doi.org/10.1172/jci.insight.158937 http://insight.jci.org/articles/view/158937/files/pdf |
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