Detection of m6A from direct RNA sequencing using a multiple instance learning framework
Abstract RNA modifications such as m6A methylation form an additional layer of complexity in the transcriptome. Nanopore direct RNA sequencing can capture this information in the raw current signal for each RNA molecule, enabling the detection of RNA modifications using supervised machine learning....
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Autori principali: | , , , , , |
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Natura: | Artigo |
Lingua: | inglese |
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2022
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Accesso online: | https://doi.org/10.1038/s41592-022-01666-1 https://www.nature.com/articles/s41592-022-01666-1.pdf |
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