Dusp6 deficiency attenuates neutrophil-mediated cardiac damage in the acute inflammatory phase of myocardial infarction

Dusp6 deficiency attenuates neutrophil-mediated cardiac damage in the acute inflammatory phase of myocardial infarction

Abstract Dual-specificity phosphatase 6 (DUSP6) serves a specific and conserved function on the dephosphorylation of extracellular signal-regulated kinase 1/2 (ERK1/2). We previously identified Dusp6 as a regenerative repressor during zebrafish heart regeneration, therefore we propose to investigate...

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Bibliografiske detaljer
Main Authors: Xiaohai Zhou, Chenyang Zhang, Xueying Wu, Xinli Hu, Yan Zhang, Xuelian Wang, Lixia Zheng, Peng Gao, Jianyong Du, Wen Zheng, Haibao Shang, Keping Hu, Zhengfan Jiang, Yu Nie, Shengshou Hu, Rui‐Ping Xiao, Xiaojun Zhu, Jing‐Wei Xiong
Format: Artigo
Sprog:engelsk
Udgivet: 2022
Online adgang:https://doi.org/10.1038/s41467-022-33631-z
https://www.nature.com/articles/s41467-022-33631-z.pdf
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https://doi.org/10.1038/s41467-022-33631-z
https://www.nature.com/articles/s41467-022-33631-z.pdf

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