ADAR activation by inducing a <i>syn</i> conformation at guanosine adjacent to an editing site
ADARs (adenosine deaminases acting on RNA) can be directed to sites in the transcriptome by complementary guide strands allowing for the correction of disease-causing mutations at the RNA level. However, ADARs show bias against editing adenosines with a guanosine 5' nearest neighbor (5'-GA...
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| Hoofdauteurs: | , , , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Engels |
| Gepubliceerd in: |
2022
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| Online toegang: | https://doi.org/10.1093/nar/gkac897 https://academic.oup.com/nar/article-pdf/50/19/10857/46844838/gkac897.pdf |
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