A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids
Abstract Amino acid availability controls mTORC1 activity via a heterodimeric Rag GTPase complex that functions as a scaffold at the lysosomal surface, bringing together mTORC1 with its activators and effectors. Mammalian cells express four Rag proteins (RagA–D) that form dimers composed of RagA/B b...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | İngilizce |
| Baskı/Yayın Bilgisi: |
2022
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| Online Erişim: | https://doi.org/10.1038/s41556-022-00976-y https://www.nature.com/articles/s41556-022-00976-y.pdf |
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