Molecular and cellular evolution of the primate dorsolateral prefrontal cortex

Molecular and cellular evolution of the primate dorsolateral prefrontal cortex

The granular dorsolateral prefrontal cortex (dlPFC) is an evolutionary specialization of primates that is centrally involved in cognition. We assessed more than 600,000 single-nucleus transcriptomes from adult human, chimpanzee, macaque, and marmoset dlPFC. Although most cell subtypes defined transc...

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Main Authors: Shaojie Ma, Mario Škarica, Qian Li, Chuan Xu, Ryan D. Risgaard, Andrew T.N. Tebbenkamp, Xoel Mato-Blanco, Rothem Kovner, Željka Krsnik, Xabier de Martin, Victor Luria, Xavier Martí-Pérez, Dan Liang, Amir Karger, Danielle K. Schmidt, Zachary Gomez-Sanchez, Qi Cai, Kevin T. Gobeske, Sirisha Pochareddy, Ashwin Debnath, Cade J. Hottman, Joshua Spurrier, Leon Teo, Anthony G. Boghdadi, Jihane Homman‐Ludiye, John J. Ely, Etienne W. Daadi, Da Mi, Marcel M. Daadi, Oscar Marı́n, Patrick R. Hof, Mladen‐Roko Rašin, James A. Bourne, Chet C. Sherwood, Gabriel Santpere, Matthew J. Girgenti, Stephen M. Strittmatter, André M. M. Sousa, Nenad Šestan
Format: Artigo
Language:English
Published: 2022
Online Access:https://doi.org/10.1126/science.abo7257
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https://doi.org/10.1126/science.abo7257

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