Systemic immunosuppression promotes survival and integration of subretinally implanted human ESC-derived photoreceptor precursors in dogs

Systemic immunosuppression promotes survival and integration of subretinally implanted human ESC-derived photoreceptor precursors in dogs

Regenerative therapies aimed at replacing photoreceptors are a promising approach for the treatment of otherwise incurable causes of blindness. However, such therapies still face significant hurdles, including the need to improve subretinal delivery and long-term survival rate of transplanted cells,...

Full description

Saved in:
Bibliographic Details
Main Authors: Ana Ripolles‐Garcia, Natalia V. Dolgova, M. Joseph Phillips, Svetlana Savina, Allison L. Ludwig, Sara A. Stuedemann, Uchenna Nlebedum, John H. Wolfe, Oliver A. Garden, Arvydas Maminishkis, Juan Amaral, Kapil Bharti, David M. Gamm, Gustavo D. Aguirre, William A. Beltran
Format: Artigo
Language:English
Published: 2022
Online Access:https://doi.org/10.1016/j.stemcr.2022.06.009
https://www.cell.com/article/S2213671122003253/pdf
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1016/j.stemcr.2022.06.009
https://www.cell.com/article/S2213671122003253/pdf

Similar Items