Optical Genome Mapping as a Diagnostic Tool in Pediatric Acute Myeloid Leukemia

Pediatric AML is characterized by numerous genetic aberrations (chromosomal translocations, deletions, insertions) impacting its classification for risk of treatment failure. Aberrations are described by classical cytogenetic procedures (karyotyping, FISH), which harbor limitations (low resolution,...

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Main Authors: Julia Suttorp, Jonathan Lukas Lühmann, Yvonne Lisa Behrens, Gudrun Göhring, Doris Steinemann, Dirk Reinhardt, Nils von Neuhoff, Markus Schneider
格式: Artigo
語言:英语
出版: 2022
在線閱讀:https://doi.org/10.3390/cancers14092058
https://www.mdpi.com/2072-6694/14/9/2058/pdf?version=1650430806
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