RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin

The small GTPase ARL8 associates with endolysosomes, leading to the recruitment of several effectors that couple endolysosomes to kinesins for anterograde transport along microtubules, and to tethering factors for eventual fusion with other organelles. Herein we report the identification of the RUN-...

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Detalhes bibliográficos
Main Authors: Tal Keren‐Kaplan, Amra Sarić, Saikat Ghosh, Chad D. Williamson, Rui Jia, Yan Li, Juan S. Bonifacino
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
Acesso em linha:https://doi.org/10.1038/s41467-022-28952-y
https://www.nature.com/articles/s41467-022-28952-y.pdf
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