Genetic variation at mouse and human ribosomal DNA influences associated epigenetic states

Genetic variation at mouse and human ribosomal DNA influences associated epigenetic states

Abstract Background Ribosomal DNA (rDNA) displays substantial inter-individual genetic variation in human and mouse. A systematic analysis of how this variation impacts epigenetic states and expression of the rDNA has thus far not been performed. Results Using a combination of long- and short-read s...

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Detalhes bibliográficos
Principais autores: Francisco Rodríguez-Algarra, Robert A. Seaborne, Amy F. Danson, Selin Yildizoglu, Harunori Yoshikawa, Pui Pik Law, Zakaryya Ahmad, Victoria A. Maudsley, Ama Brew, Nadine Holmes, Mateus Ochôa, Alan Hodgkinson, Sarah J. Marzi, Madapura M. Pradeepa, Matthew Loose, Michelle L. Holland, Vardhman K. Rakyan
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
Acesso em linha:https://doi.org/10.1186/s13059-022-02617-x
https://genomebiology.biomedcentral.com/track/pdf/10.1186/s13059-022-02617-x
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Internet

https://doi.org/10.1186/s13059-022-02617-x
https://genomebiology.biomedcentral.com/track/pdf/10.1186/s13059-022-02617-x

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