Inhibition of CDK4/6 Promotes CD8 T-cell Memory Formation
Abstract CDK4/6 inhibitors are approved to treat breast cancer and are in trials for other malignancies. We examined CDK4/6 inhibition in mouse and human CD8+ T cells during early stages of activation. Mice receiving tumor-specific CD8+ T cells treated with CDK4/6 inhibitors displayed increased T-ce...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2021
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| 在线阅读: | https://doi.org/10.1158/2159-8290.cd-20-1540 https://cancerdiscovery.aacrjournals.org/content/candisc/11/10/2564.full.pdf |
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