Human stem cell-based retina on chip as new translational model for validation of AAV retinal gene therapy vectors
Gene therapies using adeno-associated viruses (AAVs) are among the most promising strategies to treat or even cure hereditary and acquired retinal diseases. However, the development of new efficient AAV vectors is slow and costly, largely because of the lack of suitable non-clinical models. By faith...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2021
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Acesso em linha: | https://doi.org/10.1016/j.stemcr.2021.08.008 https://www.cell.com/article/S2213671121004264/pdf |
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