Quantitative analysis of genome packaging in recombinant AAV vectors by charge detection mass spectrometry

Recombinant adeno-associated virus (rAAV) has emerged as an important gene therapy vector with many clinical trials currently in progress. Analytical characterization and quantitation of particle content remain challenges in both the development and production of rAAV vectors. In this study, charge...

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Hlavní autoři: Lauren F. Barnes, Benjamin E. Draper, Yu‐Ting Chen, Thomas W. Powers, Martin F. Jarrold
Médium: Artigo
Jazyk:angličtina
Vydáno: 2021
On-line přístup:https://doi.org/10.1016/j.omtm.2021.08.002
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