Quantitative analysis of genome packaging in recombinant AAV vectors by charge detection mass spectrometry

Recombinant adeno-associated virus (rAAV) has emerged as an important gene therapy vector with many clinical trials currently in progress. Analytical characterization and quantitation of particle content remain challenges in both the development and production of rAAV vectors. In this study, charge...

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Bibliografische gegevens
Hoofdauteurs: Lauren F. Barnes, Benjamin E. Draper, Yu‐Ting Chen, Thomas W. Powers, Martin F. Jarrold
Formaat: Artigo
Taal:Engels
Gepubliceerd in: 2021
Online toegang:https://doi.org/10.1016/j.omtm.2021.08.002
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