Acquisition of the L452R Mutation in the ACE2-Binding Interface of Spike Protein Triggers Recent Massive Expansion of SARS-CoV-2 Variants

Acquisition of the L452R Mutation in the ACE2-Binding Interface of Spike Protein Triggers Recent Massive Expansion of SARS-CoV-2 Variants

We report that there is a recent global expansion of numerous independent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with mutation L452R in the receptor-binding domain (RBD) of the spike protein. The massive emergence of L452R variants was first linked to lineage B.1.427/B...

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Xehetasun bibliografikoak
Egile Nagusiak: Veronika Tchesnokova, Hemantha D. Kulasekara, Lydia Larson, Victoria Bowers, Elena Rechkina, Dagmara Kisiela, Yulia Sledneva, Debarati Choudhury, Iryna Maslova, Kai Deng, Kirthi K. Kutumbaka, Hao Geng, Curtis Fowler, Dina N. Greene, James D. Ralston, Mansour Samadpour, Evgeni V. Sokurenko
Formatua: Artigo
Hizkuntza:ingelesa
Argitaratua: 2021
Sarrera elektronikoa:https://doi.org/10.1128/jcm.00921-21
Etiketak: Etiketa erantsi
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Internet

https://doi.org/10.1128/jcm.00921-21

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