Chronological genome and single-cell transcriptome integration characterizes the evolutionary process of adult T cell leukemia-lymphoma
Abstract Subclonal genetic heterogeneity and their diverse gene expression impose serious problems in understanding the behavior of cancers and contemplating therapeutic strategies. Here we develop and utilize a capture-based sequencing panel, which covers host hotspot genes and the full-length geno...
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| Главные авторы: | , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | английский |
| Опубликовано: |
2021
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| Online-ссылка: | https://doi.org/10.1038/s41467-021-25101-9 https://www.nature.com/articles/s41467-021-25101-9.pdf |
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