BRAF Gene and Melanoma: Back to the Future
As widely acknowledged, 40–50% of all melanoma patients harbour an activating BRAF mutation (mostly BRAF V600E). The identification of the RAS–RAF–MEK–ERK (MAP kinase) signalling pathway and its targeting has represented a valuable milestone for the advanced and, more recently, for the completely re...
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| Autors principals: | , , , , , , , , , , , , , , , , |
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| Format: | Revisão |
| Idioma: | anglès |
| Publicat: |
2021
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| Accés en línia: | https://doi.org/10.3390/ijms22073474 https://www.mdpi.com/1422-0067/22/7/3474/pdf?version=1617937390 |
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