Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2
There is an urgent need for antivirals to treat the newly emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To identify new candidates, we screen a repurposing library of ∼3,000 drugs. Screening in Vero cells finds few antivirals, while screening in human Huh7.5 cells validates 2...
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Main Authors: | , , , , , , , , , , , , , , , , |
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格式: | Artigo |
语言: | 英语 |
出版: |
2021
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在线阅读: | https://doi.org/10.1016/j.celrep.2021.108959 |
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