Loss of the metabolism and sleep regulating neuronal populations expressing orexin and oxytocin in the hypothalamus in amyotrophic lateral sclerosis

Abstract Aims To determine the underlying cellular changes and clinical correlates associated with pathology of the hypothalamus in amyotrophic lateral sclerosis (ALS), as hypothalamic atrophy occurs in the preclinical phase of the disease. Methods The hypothalamus was pathologically examined in nin...

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Principais autores: Sanaz Gabery, Rebekah M. Ahmed, Jashelle Caga, Matthew C. Kiernan, Glenda M. Halliday, Åsa Petersén
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Acesso em linha:https://doi.org/10.1111/nan.12709
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/nan.12709
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