Loss of the metabolism and sleep regulating neuronal populations expressing orexin and oxytocin in the hypothalamus in amyotrophic lateral sclerosis

Abstract Aims To determine the underlying cellular changes and clinical correlates associated with pathology of the hypothalamus in amyotrophic lateral sclerosis (ALS), as hypothalamic atrophy occurs in the preclinical phase of the disease. Methods The hypothalamus was pathologically examined in nin...

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Autors principals: Sanaz Gabery, Rebekah M. Ahmed, Jashelle Caga, Matthew C. Kiernan, Glenda M. Halliday, Åsa Petersén
Format: Artigo
Idioma:anglès
Publicat: 2021
Accés en línia:https://doi.org/10.1111/nan.12709
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/nan.12709
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