Loss of the metabolism and sleep regulating neuronal populations expressing orexin and oxytocin in the hypothalamus in amyotrophic lateral sclerosis

Abstract Aims To determine the underlying cellular changes and clinical correlates associated with pathology of the hypothalamus in amyotrophic lateral sclerosis (ALS), as hypothalamic atrophy occurs in the preclinical phase of the disease. Methods The hypothalamus was pathologically examined in nin...

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Autori principali: Sanaz Gabery, Rebekah M. Ahmed, Jashelle Caga, Matthew C. Kiernan, Glenda M. Halliday, Åsa Petersén
Natura: Artigo
Lingua:inglese
Pubblicazione: 2021
Accesso online:https://doi.org/10.1111/nan.12709
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/nan.12709
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