Cas9-directed immune tolerance in humans—a model to evaluate regulatory T cells in gene therapy?
Abstract The dichotomic nature of the adaptive immune response governs the outcome of clinical gene therapy. On the one hand, neutralizing antibodies and cytotoxic T cells can have a dramatic impact on the efficacy and safety of human gene therapies. On the other hand, regulatory T cells (Treg) can...
Enregistré dans:
| Auteurs principaux: | , , |
|---|---|
| Format: | Revisão |
| Langue: | anglais |
| Publié: |
2021
|
| Accès en ligne: | https://doi.org/10.1038/s41434-021-00232-2 https://www.nature.com/articles/s41434-021-00232-2.pdf |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|