Mechanisms of Resistance to Prostate-Specific Membrane Antigen-Targeted Radioligand Therapy in a Mouse Model of Prostate Cancer

Mechanisms of Resistance to Prostate-Specific Membrane Antigen-Targeted Radioligand Therapy in a Mouse Model of Prostate Cancer

Prostate-specific membrane antigen (PSMA)–targeted radioligand therapy (RLT) is effective against prostate cancer (PCa), but all patients relapse eventually. Poor understanding of the underlying resistance mechanisms represents a key barrier to development of more effective RLT. We investigate the p...

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Hauptverfasser: Andreea D. Stuparu, Joseph Capri, Catherine Meyer, Thuc Le, Susan Evans‐Axelsson, Kyle Current, Mark Lennox, Christine E. Mona, Wolfgang P. Fendler, Jérémie Calais, Matthias Eiber, Magnus Dahlbom, Johannes Czernin, Caius G. Radu, Katharina Lückerath, Roger Slavik
Format: Artigo
Sprache:Englisch
Veröffentlicht: 2020
Online-Zugang:https://doi.org/10.2967/jnumed.120.256263
https://jnm.snmjournals.org/content/jnumed/62/7/989.full.pdf
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https://doi.org/10.2967/jnumed.120.256263
https://jnm.snmjournals.org/content/jnumed/62/7/989.full.pdf

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