Multi-center real-world comparison of the fully automated Idylla™ microsatellite instability assay with routine molecular methods and immunohistochemistry on formalin-fixed paraffin-embedded tissue of colorectal cancer

Multi-center real-world comparison of the fully automated Idylla™ microsatellite instability assay with routine molecular methods and immunohistochemistry on formalin-fixed paraffin-embedded tissue of colorectal cancer

Abstract Microsatellite instability (MSI) is present in 15–20% of primary colorectal cancers. MSI status is assessed to detect Lynch syndrome, guide adjuvant chemotherapy, determine prognosis, and use as a companion test for checkpoint blockade inhibitors. Traditionally, MSI status is determined by...

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Κύριοι συγγραφείς: Ana Velasco, Fatma Tokat, Jesper Bonde, Nicola Trim, Elisabeth Bauer, Adam Meeney, Wendy de Leng, George Chong, Véronique Dalstein, Lóránd Kis, Jon A. Lorentzen, Snježana Tomić, Keeley Thwaites, Martina Putzová, Astrid Birnbaum, Romena Qazi, Vanessa Primmer, Barbara Dockhorn‐Dworniczak, Javier Hernández‐Losa, Fernando Augusto Soares, Asaf A. Gertler, Michal Kalman, Chris Wong, Dirce Maria Carraro, Ana Carla Sousa, Rui Manuel Reis, Stephen B. Fox, Matteo Fassan, Marie Brevet, Sabine Merkelbach‐Bruse, Richard Colling, Elizabeth J. Soilleux, Ryan Yee Wei Teo, Nicky D’Haene, Serge Nolet, Ari Ristimäki, Timo Väisänen, Caroline Chapusot, Afsaneh Soruri, Tina Unger, Johanna Wecgowiec, Michele Biscuola, Milo Frattini, Anna Long, Paulo Vidal Campregher, Xavier Matías‐Guiu
Μορφή: Artigo
Γλώσσα:Αγγλικά
Έκδοση: 2020
Διαθέσιμο Online:https://doi.org/10.1007/s00428-020-02962-x
https://link.springer.com/content/pdf/10.1007/s00428-020-02962-x.pdf
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https://doi.org/10.1007/s00428-020-02962-x
https://link.springer.com/content/pdf/10.1007/s00428-020-02962-x.pdf

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