p53 drives a transcriptional program that elicits a non-cell-autonomous response and alters cell state in vivo
Significance Although p53 is highly studied, the molecular and physiological consequences of the p53 transcriptional response are poorly understood. Through RNA sequencing of multiple mouse tissues upon genetic activation of p53, we identified hundreds of tissue-specific p53 target genes and a set o...
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| Автори: | , , , , , |
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| Формат: | Artigo |
| Мова: | Англійська |
| Опубліковано: |
2020
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| Онлайн доступ: | https://doi.org/10.1073/pnas.2008474117 https://www.pnas.org/content/pnas/117/38/23663.full.pdf |
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