Triacylglycerol synthesis enhances macrophage inflammatory function

Abstract Foamy macrophages, which have prominent lipid droplets (LDs), are found in a variety of disease states. Toll-like receptor agonists drive triacylglycerol (TG)-rich LD development in macrophages. Here we explore the basis and significance of this process. Our findings indicate that LD develo...

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Príomhchruthaitheoirí: Ângela Castoldi, Lauar de Brito Monteiro, Nikki van Teijlingen Bakker, David E. Sanin, Nisha Rana, Mauro Corrado, Alanna M. Cameron, Fabian Hässler, Mai Matsushita, George Caputa, Ramon I. Klein Geltink, Jörg Büscher, Joy Edwards-Hicks, Erika L. Pearce, Edward J. Pearce
Formáid: Artigo
Teanga:Béarla
Foilsithe / Cruthaithe: 2020
Rochtain ar líne:https://doi.org/10.1038/s41467-020-17881-3
https://www.nature.com/articles/s41467-020-17881-3.pdf
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