Potential anti-neuroinflammatory NF-кB inhibitors based on 3,4-dihydronaphthalen-1(2<i>H</i>)-one derivatives

Nuclear factor kappa B (NF-кB) inhibition represents a new therapeutic strategy for the treatment of neuroinflammatory diseases. In this study, a series of 3,4-dihydronaphthalen-1(2H)-one (DHN; 6a-n, 7a-c) derivatives were synthesised and characterised by NMR and HRMS. We assessed the toxicity and a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yue Sun, Yan-Qiu Zhou, Yin-Kai Liu, Hongqin Zhang, Gui‐Ge Hou, Qingguo Meng, Yun Hou
Fformat: Artigo
Iaith:Saesneg
Cyhoeddwyd: 2020
Mynediad Ar-lein:https://doi.org/10.1080/14756366.2020.1804899
https://www.tandfonline.com/doi/pdf/10.1080/14756366.2020.1804899?needAccess=true
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!