Potential anti-neuroinflammatory NF-кB inhibitors based on 3,4-dihydronaphthalen-1(2<i>H</i>)-one derivatives
Nuclear factor kappa B (NF-кB) inhibition represents a new therapeutic strategy for the treatment of neuroinflammatory diseases. In this study, a series of 3,4-dihydronaphthalen-1(2H)-one (DHN; 6a-n, 7a-c) derivatives were synthesised and characterised by NMR and HRMS. We assessed the toxicity and a...
Wedi'i Gadw mewn:
Prif Awduron: | , , , , , , |
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Fformat: | Artigo |
Iaith: | Saesneg |
Cyhoeddwyd: |
2020
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Mynediad Ar-lein: | https://doi.org/10.1080/14756366.2020.1804899 https://www.tandfonline.com/doi/pdf/10.1080/14756366.2020.1804899?needAccess=true |
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