Growth differentiation factor 15 protects against the aging‐mediated systemic inflammatory response in humans and mice

Abstract Mitochondrial dysfunction is associated with aging‐mediated inflammatory responses, leading to metabolic deterioration, development of insulin resistance, and type 2 diabetes. Growth differentiation factor 15 (GDF15) is an important mitokine generated in response to mitochondrial stress and...

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Bibliographic Details
Main Authors: Ji Sun Moon, Ludger J.E. Goeminne, Jung Tae Kim∥, Jing Tian, Seok‐Hwan Kim, Ha Thi Nga, Seulgi Kang, Baeki E. Kang, Jin‐Seok Byun, Young‐Sun Lee, Jae‐Han Jeon, Minho Shong, Johan Auwerx, Dongryeol Ryu, Hyon‐Seung Yi
Format: Artigo
Language:English
Published: 2020
Online Access:https://doi.org/10.1111/acel.13195
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/acel.13195
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