Motor cortex transcriptome reveals microglial key events in amyotrophic lateral sclerosis

Motor cortex transcriptome reveals microglial key events in amyotrophic lateral sclerosis

<h3>Objective</h3> To identify transcriptomic changes, neuropathologic correlates, and cellular subpopulations in the motor cortex of sporadic amyotrophic lateral sclerosis (ALS). <h3>Methods</h3> We performed massive RNA sequencing of the motor cortex of patients with ALS (n...

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Auteurs principaux: Oriol Dols‐Icardo, Víctor Montal, Sònia Sirisi, Gema López‐Pernas, Laura Cervera‐Carles, Marta Querol‐Vilaseca, Laia Muñoz, Olivia Belbin, Daniel Alcolea, Laura Molina‐Porcel, Jordi Pegueroles, Janina Turón‐Sans, Rafael Blesa, Alberto Lleó, Juan Fortea, Ricard Rojas‐García, Jordi Clarimón
Format: Artigo
Langue:anglais
Publié: 2020
Accès en ligne:https://doi.org/10.1212/nxi.0000000000000829
https://nn.neurology.org/content/nnn/7/5/e829.full.pdf
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Internet

https://doi.org/10.1212/nxi.0000000000000829
https://nn.neurology.org/content/nnn/7/5/e829.full.pdf

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