Modulation of gut microbiota to overcome resistance to immune checkpoint blockade in cancer immunotherapy

Immune checkpoint blockade therapies that target CTLA-4 and PD-1/PD-L1 have ushered in a new era of cancer treatment. Nevertheless, a significant proportion of patients demonstrated primary or acquired resistance. Harnessing gut microbiota has been an emerging novel therapeutic strategy to overcome...

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Auteurs principaux: Jumin Huang, Zebo Jiang, Yuwei Wang, Xiaoqing Fan, Jun Cai, Xiaojun Yao, Liang Liu, Jun Huang, Jianxing He, Chun Xie, Qibiao Wu, Yabing Cao, Elaine Lai‐Han Leung
Format: Revisão
Langue:anglais
Publié: 2020
Accès en ligne:https://doi.org/10.1016/j.coph.2020.06.004
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