Modulation of gut microbiota to overcome resistance to immune checkpoint blockade in cancer immunotherapy
Immune checkpoint blockade therapies that target CTLA-4 and PD-1/PD-L1 have ushered in a new era of cancer treatment. Nevertheless, a significant proportion of patients demonstrated primary or acquired resistance. Harnessing gut microbiota has been an emerging novel therapeutic strategy to overcome...
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Auteurs principaux: | , , , , , , , , , , , , |
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Format: | Revisão |
Langue: | anglais |
Publié: |
2020
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Accès en ligne: | https://doi.org/10.1016/j.coph.2020.06.004 |
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