Systematic Investigation of the Permeability of Androgen Receptor PROTACs
Bifunctional molecules known as PROTACs simultaneously bind an E3 ligase and a protein of interest to direct ubiquitination and clearance of that protein, and they have emerged in the past decade as an exciting new paradigm in drug discovery. In order to investigate the permeability and properties o...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2020
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| 在线阅读: | https://doi.org/10.1021/acsmedchemlett.0c00194 |
| 标签: |
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