Systematic Investigation of the Permeability of Androgen Receptor PROTACs

Bifunctional molecules known as PROTACs simultaneously bind an E3 ligase and a protein of interest to direct ubiquitination and clearance of that protein, and they have emerged in the past decade as an exciting new paradigm in drug discovery. In order to investigate the permeability and properties o...

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書誌詳細
主要な著者: Duncan E. Scott, Timothy P. C. Rooney, Elliott D. Bayle, Tashfina Mirza, Henriëtte M. G. Willems, Jonathan H. Clarke, Stephen P. Andrews, John Skidmore
フォーマット: Artigo
言語:英語
出版事項: 2020
オンライン・アクセス:https://doi.org/10.1021/acsmedchemlett.0c00194
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