Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation

Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation

Abstract The exopolysaccharide galactosaminogalactan (GAG) is an important virulence factor of the fungal pathogen Aspergillus fumigatus . Deletion of a gene encoding a putative deacetylase, Agd3, leads to defects in GAG deacetylation, biofilm formation, and virulence. Here, we show that Agd3 deacet...

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Xehetasun bibliografikoak
Egile Nagusiak: Natalie C. Bamford, François Le Mauff, Jaime C. Van Loon, Hanna Ostapska, Brendan D. Snarr, Yongzhen Zhang, Elena N. Kitova, John S. Klassen, Jeroen D. C. Codée, Donald C. Sheppard, P. Lynne Howell
Formatua: Artigo
Hizkuntza:ingelesa
Argitaratua: 2020
Sarrera elektronikoa:https://doi.org/10.1038/s41467-020-16144-5
https://www.nature.com/articles/s41467-020-16144-5.pdf
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Internet

https://doi.org/10.1038/s41467-020-16144-5
https://www.nature.com/articles/s41467-020-16144-5.pdf

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