Genetic characterization of a unique neuroendocrine transdifferentiation prostate circulating tumor cell-derived eXplant model

Genetic characterization of a unique neuroendocrine transdifferentiation prostate circulating tumor cell-derived eXplant model

Transformation of castration-resistant prostate cancer (CRPC) into an aggressive neuroendocrine disease (CRPC-NE) represents a major clinical challenge and experimental models are lacking. A CTC-derived eXplant (CDX) and a CDX-derived cell line are established using circulating tumor cells (CTCs) ob...

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Autori principali: Vincent Faugeroux, Emma Pailler, Marianne Oulhen, Olivier Déas, Laura Brullé-Soumaré, Céline Hervieu, Virginie Marty, Kamélia Alexandrova, Kiki Andree, Nikolas H. Stoecklein, Dominique Tramalloni, Stefano Cairo, Maud Ngo‐Camus, Claudio Nicotra, Leon W.M.M. Terstappen, Nicolò Manaresi, Valérie Lapierre, Karim Fizazi, Jean–Yves Scoazec, Yohann Loriot, Jean‐Gabriel Judde, Françoise Farace
Natura: Artigo
Lingua:inglese
Pubblicazione: 2020
Accesso online:https://doi.org/10.1038/s41467-020-15426-2
https://www.nature.com/articles/s41467-020-15426-2.pdf
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https://doi.org/10.1038/s41467-020-15426-2
https://www.nature.com/articles/s41467-020-15426-2.pdf

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