Erythrocyte Metabolic Reprogramming by Sphingosine 1-Phosphate in Chronic Kidney Disease and Therapies

Erythrocyte Metabolic Reprogramming by Sphingosine 1-Phosphate in Chronic Kidney Disease and Therapies

Hypoxia promotes renal damage and progression of chronic kidney disease (CKD). The erythrocyte is the only cell type for oxygen (O2) delivery. Sphingosine 1-phosphate (S1P)-a highly enriched biolipid in erythrocytes-is recently reported to be induced under high altitude in normal humans to enhance O...

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Hlavní autoři: Tingting Xie, Chang‐Han Chen, Zhangzhe Peng, Benjamin C. Brown, Julie A. Reisz, Ping Xu, Zhen Zhou, Anren Song, Yujin Zhang, Mikhail Bogdanov, Rodney E. Kellems, Angelo D’Alessandro, Weiru Zhang, Yang Xia
Médium: Artigo
Jazyk:angličtina
Vydáno: 2020
On-line přístup:https://doi.org/10.1161/circresaha.119.316298
https://www.ahajournals.org/doi/pdf/10.1161/CIRCRESAHA.119.316298
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https://doi.org/10.1161/circresaha.119.316298
https://www.ahajournals.org/doi/pdf/10.1161/CIRCRESAHA.119.316298

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